Framework Ventures is a venture capital firm based in San Francisco, California that framework ventures is a crypto-native venture capital firm founded in 2019 by vance spencer and michael anderson, based in san francisco. it makes high-conviction, early-stage investments in blockchain, defi, gaming and related emerging technologies, with typical check sizes ranging from about 5 million to 40 million dollars. the firm has expanded its thesis toward frontier technologies spanning blockchain infrastructure, artificial intelligence and real-world industrial applications. it held around 1.28 billion dollars in assets under management as of december 2025 per sec filings. framework raised 100 million dollars for its second fund in 2021, 400 million dollars for its third fund, and 400 million dollars for a fourth fund announced in 2026. They serve clients in United States. Framework Ventures is listed on The Token Playbook's vetted provider registry at thetokenplaybook.com/registry/framework-ventures.